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Potential therapeutic target for wound-healing and cancer identified

A Jackson Laboratory research team led by Professor Lenny Shultz, Ph.D., reports that a protein involved in wound healing and tumor growth could be a potential therapeutic target.

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Dopamine and hippocampus

Bruno Giros, PhD, a researcher at the Douglas Mental Health University Institute and a professor in the Department of Psychiatry at McGill University, has demonstrated, for the first time, the role...

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Why some experimental forms of 'The Pill for Males' will never rise to the...

It appears that "The Pill" for men will have to wait a while longer. A new research report published in the June 2014 issue of The FASEB Journal involving mice, shows that a previously developed male...

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Brain scientist continues exploring the brain

A Montana State University assistant professor in neuroscience is part of a team that has made progress understanding how the brain processes visual information. In addition to adding to the basic...

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'Big data' technique improves monitoring of kidney transplant patients

A new data analysis technique could radically improve monitoring of kidney transplant patients, according to new research published this week in PLOS Computational Biology.

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Scientists uncover new compounds that could affect circadian rhythm

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have discovered a surprising new role for a pair of compounds—which have the potential to alter circadian rhythm, the complex...

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Treatment for overactive bladder and irritable bowel syndrome advanced...

Researchers at the University of Surrey have discovered how the receptors responsible for contractions in the bladder, regulate the body's clock genes.

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Dyslexic readers have disrupted network connections in the brain

Dyslexia, the most commonly diagnosed learning disability in the United States, is a neurological reading disability that occurs when the regions of the brain that process written language don't...

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Over-the-counter pain reliever may restore immune function in old age

New research involving mice suggests that the key to more youthful immune function might already be in your medicine cabinet. In a report published in the Journal of Leukocyte Biology scientists show...

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Adolescent exposure to THC may cause immune systems to go up in smoke

When it comes to using marijuana, new research, involving mice and published in the October 2014 issue of the Journal of Leukocyte Biology, suggests that just because you can do it, doesn't mean that...

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The effects of poor eating habits persist even after diet is improved

Almost everyone knows that improving your eating habits will most likely improve your health. What most people may not know, however, is that the effects of poor eating habits persist long after...

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Animal study points to a treatment for Huntington's disease

By adjusting the levels of a key signaling protein, researchers improved motor function and brain abnormalities in experimental animals with a form of Huntington's disease, a severe neurodegenerative...

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Study identifies biological mechanisms for schizophrenia, bipolar disorder...

Common psychiatric disorders such as schizophrenia, bipolar disorder and major depression share genetic risk factors related to immune function and DNA regulation, according to new findings by a large...

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How NORE1A acts as a barrier to tumor growth

Researchers reveal how cells protect themselves from a protein that is a key driver of cancer. The study appears in The Journal of Cell Biology.

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Tool to analyze genes according to their evolutionary profiles

Two major revolutions, one genomic and one in informatics, are completely changing the face of biomedical research. Every day all over the world, millions of genetic sequences—from disease-related...

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Team identifies viral product that promotes immune defense against RSV

Almost all human beings are exposed to the respiratory syncytial virus, or RSV, before their second birthdays. For most, the symptoms mimic those of the common cold: runny nose, coughing, sneezing,...

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Image: How stem cells create just enough tissue

Scientists have long wondered just how stem cells generate just the right amount of tissue to perform a biological function. Using live imaging of skin of living mice, Yale scientists have shown that...

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Changes in brain networks may help youth adapt to childhood adversity

A new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging reports a neural signature of emotional adaptation that could help researchers understand how the brain adapts to childhood...

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Brain alterations support categorical and dimensional features of the...

A study in Biological Psychiatry provides a new understanding of brain alterations in children with autism spectrum disorder (ASD) that may help researchers and clinicians better define the disorder.

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New computational tool could help match kidney donors to recipients

A new scoring system that compares the genetic matching of kidney donors and recipients could help improve predictions of transplant success, according to a study published in PLOS Computational Biology.

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Missed connections: As people age, memory-related brain activity loses cohesion

Groups of brain regions that synchronize their activity during memory tasks become smaller and more numerous as people age, according to a study published in PLOS Computational Biology.

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Study reveals areas of the brain impacted by PTSD

Researchers at Boston University School of Medicine (BUSM) and the VA Boston Healthcare System are one step closer to understanding the specific nature of brain changes associated with Posttraumatic...

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A common medication restores social deficits in autism mouse model

Reducing the function of the autism-associated gene Pcdh10 leads to impairments in social behavior, according to a study published in Biological Psychiatry. Reducing Pcdh10 function also disrupted the...

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Emphysema treatment could be optimized using network modelling

A unique engineering perspective of emphysema progression in the lung suggests how mechanisms operating at the micromechanical scale could help to predict patient survival and quality of life following...

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Researchers find new mechanism essential for maintaining breathing rhythm;...

In a new study published in the journal Neuron, a group of researchers at Baylor College of Medicine, Texas Children's Hospital, Washington University and the University of Pennsylvania reveal a new...

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What Netflix can teach us about treating cancer

Two years ago, former President Barack Obama announced the Precision Medicine initiative in his State of the Union Address. The initiative aspired to a "new era of medicine" where disease treatments...

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Possible new tool for first responders: An ice bag to the face

A new study suggests a simple bag of ice water applied to the face could help maintain adequate blood pressure in people who have suffered significant blood loss. Blair Johnson, PhD, assistant...

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Close or far, how smell tells us it's popcorn

People know a smell is popcorn whether it is cooking down the hallway or held right under their noses. Yale researchers Douglas Storace and Lawrence Cohen in the Department of Cellular and Molecular...

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Gene therapy to correct surfactant protein B deficiency in newborns

An article published in Experimental Biology and Medicine (Volume 242, Issue 13, July, 2017) reports that gene therapy may be used to as an intermediate therapy for newborns with surfactant protein...

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New virtual model reveals details of declining lung function in mice

Scientists have developed a new virtual model of mouse lung function that illuminates the relative importance of different factors that contribute to lung changes accompanying chronic inflammation....

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